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ScienceNature17h ago

Diverse binding poses of agonistic neurotoxins on human Na<sub>v</sub>1.6

Nature, Published online: 10 June 2026; doi:10. 1038/s41586-026-10661-x Structures of the distinct binding poses of three agonistic peptide toxins—bullet-ant-derived toxin δ-paraponeritoxin-Pc1a, cone snail ι-conotoxin RXIA and the globular β-scorpion toxin Cn2—on the human Nav1. 6–β1 channel com...