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Wed, Jun 10 05:58 PM

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ScienceNature17h ago

Diverse binding poses of agonistic neurotoxins on human Na<sub>v</sub>1.6

Nature, Published online: 10 June 2026; doi:10. 1038/s41586-026-10661-x Structures of the distinct binding poses of three agonistic peptide toxins—bullet-ant-derived toxin δ-paraponeritoxin-Pc1a, cone snail ι-conotoxin RXIA and the globular β-scorpion toxin Cn2—on the human Nav1. 6–β1 channel com...

ScienceNature17h ago

Gene ancestries reveal diverse microbial associations during eukaryogenesis

Nature, Published online: 10 June 2026; doi:10. 1038/s41586-026-10639-9 Phylogenomic reconstruction of the proteome of the last eukaryotic common ancestor sheds light on the origin of eukaryotes, indicating an important role of horizontal transfer of genes from diverse bacterial and viral donors.